BRIEFLY DISCUSS THE BODY FLUID COMPARTMENTS, WHAT IS THE MAJOR DIFFERENCE IN IONIC DISTRIBUTION BETWEEN EXTRACELLULAR FLUID AND INTRACELLULAR FLUID

 

SUBJECT: PHYSIOLOGY

TOPIC: CELL PHYSIOLOGY
WRITER: GOGO ANDREW MNGUTSWENGA ‘amblo

QUESTION 17
BRIEFLY DISCUSS THE BODY FLUID COMPARTMENTS, WHAT IS THE MAJOR DIFFERENCE IN IONIC DISTRIBUTION BETWEEN EXTRACELLULAR FLUID AND INTRACELLULAR FLUID

The smallest unit of the body is the cell. There are about 100 trillion cells in the body, 25% of the body cells are red blood cells, while 75% goes to other cells. There are spaces within and outside those cells that make up the body compartments.


BODY SPACES
Extracellular space – occupied by extracellular fluid
Intra cellular space – occupied by intracellular fluid

EXTRACELLULAR SPACE
It is the space outside the body with extra cellular fluid, it is divided into;
Blood plasma 
Interstitial fluid
The volume of extracellular fluid is 14 litres, the volume of intracellular fluid is 28 litres, the volume of blood plasma is 35 litres. It contains large amount of sodium, calcium, HCO-3 and nutrients for cell, waste products are present too.
 It is measured theoretically by the use of dye (substances injected in the space)


INTRACELLULAR SPACE
It is the space inside the cell, it contains intracellular fluid, the volume is 28 litres. It contains large amount of potassium, magnesium and PO4. It Is measured by taking the difference between extracellular fluid and total body water.

 The extracellular fluid differs significantly from the intracellular fluid, In that it contains larger amount of sodium and calcium instead of potassium and magnesium

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